Decrease funding for AIDS

Health and AIDS

The fight against AIDS is also suffering the effects of the global economic crisis, which is to scam the solidarity of governments. A report by the Kaiser Family Foundation and UNAIDS indicates that investments to combat the disease fell 10% in 2010, jeopardizing plans for prevention and treatment.
This is the first time that decreases funding to combat HIV / AIDS since many rich countries decide to make a financial effort to control the infection in the world's poorest areas. "This raises questions about the future of the fight against the epidemic," the report said.
Of the 15 countries surveyed, seven-Australia, Germany, Netherlands, Norway, Sweden, USA and Spain, contributed less money to this cause in 2010 than in previous years. The governments of some of these countries announced their decision to cut or freeze their contributions to the Global Fund to Fight AIDS and health, Tuberculosis and Malaria, the most important organization in this area, after the fraud detected.

Founds AIDS and Health

However, "AIDS is to invest in smart even in a difficult economic environment," says Michael Sidibe, UNAIDS Executive Director. "We must look beyond the short-term costs and recognize the long-term benefits. Donors should commit now and fulfill their promises to reduce costs in the future."
In all, 2010 is 6,900 million dollars raised for the fight against HIV / AIDS, compared with 7,600 million 2009, which were considered insufficient to maintain the policies of prevention, treatment, care and aid in the Third World .

This decrease of 740 million in investment is mainly explained by the decline in the contribution of the U.S., the world's largest donor by far. From an investment of 4,400 million in 2009, a year after Washington granted only 3,700, although as the report said, some funds committed for the last year will be distributed later under new models of collaboration established with the recipient countries and the health and AIDS.

"With U.S. funding delayed but not eliminated, the decrease in spending this year will be a temporary problem, but its impact on services will be real," stressed Drew Altman, president and CEO of the Kaiser Family Foundation.

Are any organ transplants between HIV-positive?



Around the world, carrying the HIV virus is an absolute contraindication to organ donation. However, if the recipient of the transplant is also HIV, why not allow a donation from them? That is the possibility that are being raised in the U.S. to circumvent the lack of organs, as announced this week the newspaper 'The New York Times.
For years now carrying the AIDS virus is no longer contraindicated in order to receive an organ transplant, as he explains Dr. Rafael Matesanz, general coordinator of the National Transplant Organization (ONT). However, the rejection of these patients as potential donors has been practically "a dogma of faith," and in fact, in countries like the U.S. itself is prohibited by law.

Transplant in the HIV- Positive

Elmi Muller has been a South African specialist, the first to break with this doctrine and see the success of performing transplants between HIV-positive patients (undetectable viral load and a number of requirements, as they both have the same serotype). "Keep in mind that there is a massive shortage of organs and a very large percentage of the population HIV positive," said Matesanz.

If there was any place in the world where this technique could be done more good than harm that was South Africa, as demonstrated by the results of Muller in the journal The New England Journal of Medicine. Although as Matesanz is quick to clarify, is a possibility that Spain is not even on the table. "If a living donor with HIV is offered to donate to another receptor positive, do not accept it," he says flatly. "Today is not justified."
However, it seems that the U.S. does not close the door entirely to repeal the law prohibiting it and institutions such as the Centers for Disease Control (CDC) are favorable to further investigate the risks and benefits of transplanting organs between donor and recipient carry the AIDS virus.

Organ Transplant and HIV

And it's not forget that these patients continue to have more risk than the general population, although Spain can boast of being the spearhead of transplants to seropositive recipients (previously rejected for fear of the effects could be immunosuppressive medication). "The first kidney was us, and the broader experience with liver is Spanish. In addition, a few months ago the first lung was transplanted to an HIV positive in Spain."

Today, despite the impossibility of giving, having HIV is no longer an absolute incompatibility to receive an organ. And it is not ruled out, at least in some exceptional cases, let it be a donor in the future.

The "good" cholesterol protects against colon cancer


Have high levels of good cholesterol can not only protect against cardiovascular disease and Alzheimer's. Now a new study reveals another advantage: We are defended against colon cancer. "A good reason to pay attention to the numbers of blood cholesterol," says Bas Bueno de Mesquita, the National Public Health Institute of the Netherlands and author of the study, published in the journal 'Gut'.
It was already known that people with high cholesterol are more likely to develop colon cancer. However, so far, "there had been no prospective studies which take into account the different types of lipoproteins (HDL-cholesterol known as' good'-, LDL-commonly-called bad cholesterol, triglycerides, apoA, apo B) and its role in this tumor, "says Carlos Gilsanz, Head of Service of Internal Medicine, Hospital Gregorio Maranon de Madrid.

Colon Cancer

As stated Bueno de Mesquita, "we note that for every increase of 16.6 milligrams per deciliter (mg / dl) of HDL and 32 mg / dl for apoA, try them to suffer the colon cancer were reduced by between 22% and 18% respectively. "

Although the reasons are still unknown, researchers have several theories. They point to anti-inflammatory properties of HDL and also believe that "a low concentration of this 'good' cholesterol increases oxidative stress and, therefore, the destruction of cells, which may involve the onset of cancer." At the moment only assumptions and more studies are needed to inquire about this issue and the colon cancer.
To develop this study, which also involved a number of Spanish researchers have analyzed the profiles of 1,238 people with colorectal cancer (779 with colon tumor-affected and 459 rectal) and as many healthy. All were enrolled in a European investigation into cancer and nutrition conducted in 10 countries (EPIC study).

Health and the Colon Cancer

After examining their blood, their diet and lifestyle, the results were obvious. Those with high levels of HDL cholesterol had a lower risk of colon cancer, "regardless of other markers are also associated with this tumor, such as inflammation or insulin resistance," the authors note in their article. Moreover, "we did not observe association with rectal cancer."

Given the results, could be considered "good" cholesterol as an appropriate tool to mitigate the risk of colon cancer. To get to raise their levels, explains Dr. Gilsanz, "it is best to exercise, avoid saturated fats and even take a little wine at dinner, but genetics is also important in the health.

People with HIV before age 10 years

Patients infected with Human Immunodeficiency Virus (HIV) age between 10 and 15 years faster than the normal population due to several factors, such as side effects of drugs used and the waste of the virus itself.

The acceleration of the normal physiological process of aging system of people with HIV is one of the subjects 'hot' specialists who study AIDS, explained Dr. Josep Maria Gatell, Chief of Infectious Diseases and AIDS of Hospital Clinic Barcelona . Gatell, along with Dr. Laura Waters, Royal Sussex County Hospital in Brighton (UK), and Dr. Xavier Forns, MD Consultant of Hepatology Clinic Hospital, presented the sixteenth edition of the International AIDS Symposium, to be held tomorrow Castelldefels (Barcelona).

According Gatell, antiretroviral therapy normalizes much infection in AIDS patients but it must analyze the patient's life, and that patients make an aging population and makes it "more quickly than that indicated by your ID" he explained. "As a result, have faster and more often age-related complications, such as cardiovascular disease, stroke or stroke-some varieties of cancer or a neuro-cognitive impairment.

HIV Health

As regards the treatment of infection, antiretroviral therapy is now becoming easier and better tolerated, added the specialist, but has indicated that it should be for life, representing an expenditure of between 7,000 and 8,000 euros year.
Asked if the economic crisis affect the continuity of these expensive treatments, the medical expert has held that "probably will ask us to take the greatest cost-efficiency", which is made possible by the score of existing drugs on the market treat AIDS.
In addition to premature aging of the HIV infected, the meeting will also address how to treat patients who also have hepatitis C is also a situation experienced by between 30% and 40% of AIDS patients in Spain.

Dr. Xavier Forn explained that in a few months have medications that can directly inhibit the life cycle of hepatitis C, and that associated with standard therapy for treatment of the disease, is expected to increase very significantly the cure rate.
Until now, getting existing treatments to cure between 40 and 50% of patients with hepatitis C, a rate that is expected to increase in some specific virus of this disease and who have not been treated previously.

People with HIV

Gatell noted that "the patient with HIV and hepatitis C are two problems which enhance each other, so care must be taken in parallel and simultaneously managing both diseases."
New drugs to combat hepatitis C will mean an added cost of between 6,000 and 8,000 per year although in this case Forns explained that "progress has been made in predicting the response of patients and in 12 weeks you can assess whether the disease is on the road to healing. "

In Spain, there are an estimated 130,000 people infected with HIV, of which 30% do not know that they are therefore more likely to transmit the virus to others.
This proportion is even higher in the former countries of Eastern Europe, where two of every three people infected do not know, so that neither medical nor take precautions to prevent further transmissions. This bag of people unfamiliar with the disease are responsible for the transmission of up to 70% of new cases, so that reasons of public health to improve diagnostic tests, as in the UK when it occurs a traffic accident.